Bioengineering of Corneal Stroma

Restoration of vision in scarred corneas usually involves cornea transplantation using donated tissues.
The supplies of such tissues are dwindling and very limited in many parts of the world spurring interest in artificial corneas.
The CCBL has found that adult stem cells produce a cornea-like tissue but it is not abundant or organized enough to serve as a corneal replacement.
The goals of this project are to use electrospun polymeric scaffolding to help organize tissue secreted by corneal stem cells in order to produce a transparent bioengineered corneal substitute.

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