"Characterization of the RPE Stem Cell"

November 7, 2012 -
11:45am to 1:00pm

The Fox Center for Vision Restoration organizes an exciting lecture series focusing on ocular regeneration and new therapies.

Distinguished national and international speakers present their innovative and multidisciplinary approaches to finding cures for vision impairment. The objective of this lecture series is to accelerate research through knowledge sharing, partnership building and out of the box thinking.

Jeffrey Stern, MD, PhDJeffrey Stern
Founder of the Neural Stem Cell Institute, Albany NY, and the Head of Translational Research
November 7, 11:45am – 1:00pm
(Please RSVP to baurothr@upmc.edu)

Dr. Stern earned his bachelor's degree in biology and his PhD in biophysics from Brandeis University. He did post doc work at Rockefeller University in New York before he earned his MD from the University of Miami.  He did his internship and residency at Albany Medical Center, and a fellowship at Mount Sinai Medical Center, where he focused on the retina.

Dr. Stern's research focuses on on pivotal retinal and brain stem cells. He main interest is in caring for those with diabetic retinopathy, macular degeneration, macular puckers and holes, retinal detachments and complications of cataract surgery.

More information

Presentation abstract

The proliferative potential of the retinal pigment epithelium arises from a subpopulation of RPE cells capable of self-renewal and differentiation into a variety of progeny types. Evidence indicating that RPE cells can be activated to display these cardinal features of a stem cell will be reviewed. RPESC progeny differentiated into physiologic RPE cells provide a source tissue for RPE replacement therapy. In addition, stressed RPESC differentiate into pathologic phenotypes expressing key aspects of macular degeneration and proliferative vitreoretinopathy used to screen drug candidates for therapy of these conditions.

Location and Address

Eye and Ear Boardroom, 5th floor, Eye and Ear Institute
203 Lothrop Street, Pittsburgh PA 15213