Our Mission

The Louis J. Fox Center for Vision Restoration (Fox Center) of UPMC and the University of Pittsburgh is the first national, comprehensive, multi-disciplinary research and clinical program dedicated to ocular regenerative medicine.


The Fox Center focuses on the restoration of sight through tissue regeneration, transplantation and technology. We optimize quality of life for those challenged by vision loss. We insure that individuals and their loved ones know they are not alone in addressing this challenge.

We seek to maximize participation in work, community, and society of those who lose their sight for any reason. Finally, we educate the sighted community on the prevalence of vision loss in America and around the world.



To discover and develop new cures for blindness and impairment through basic and clinical research. We focus on problems affecting the retina, optic nerve, cornea, and lens.


To restore hope and improve the quality of life for those currently suffering from vision loss. The Fox Center will provide vision restoration through the augmentation of existing visual pathways or by providing vision through sensory substitution.

Areas of specialization:

The Fox Center specializes in the five most common and important disease areas associated with vision loss:

  • Macular disease (retinal degenerations including macular degeneration, retinal vein and artery occlusion)
  • Glaucoma
  • Diabetic retinopathy
  • Optic nerve disorders
  • Corneal scarring
  • Ocular trauma
  • Sensory substitution

Strategies to achieve objectives:

  • Identifying new methods to stabilize active eye disease
  • Improving vision in patients in whom active eye disease has been stabilized, but vision remains poor
  • Providing the best possible care for patients suffering from vision impairment
  • Performing innovative research in ocular regeneration and vision rehabilitation
  • Discovering new treatments to maximize vision recovery and function
  • Educating health care professionals and patients on issues related to vision loss

Partnering with outstanding healthcare organizations

The Fox Center is a joint program of UPMC Eye Center and the McGowan Institute for Regenerative Medicine of the University of Pittsburgh.

UPMC Eye Center is a focal point for vision research nationally with fundamental expertise in research within fields of critical importance to the Fox Center. The McGowan Institute is internationally recognized for research and clinical translation of regenerative medicine-based therapies.

Against the backdrop of a rich research environment provided by the University of Pittsburgh and UPMC, the Fox Center has the capability of making a critical impact on research and patient care practices. We can thus improve the lives of people throughout the nation and around the world.

Providing hope

Vision impairment is one of the ten most frequent causes of disability in America, providing powerful motivation to advance vision rehabilitation. There is a growing need in the United States, and the world, for improvements in the quality of care for individuals suffering from a variety of vision impairments.

Whether the impairment is the result of disease or trauma, the needs of patients are poorly addressed based on the current state of patient care. Impairments represent a significant burden on families coupled with genuine loss of human potential for the community and workplace.

Every day the burden of blindness and vision impairment continues to grow. There is a burgeoning population of patients. Our understanding of regenerative research and translation, tissue engineering, cell therapy, gene therapy and stem cell transplantation has reached an unprecedented level.

We will provide hope and restore high-quality lives.